• Fine-mapping host genetic variation underlying outcomes to Mycobacterium bovis infection in dairy cows 

  Wilkinson, S.; Bishop, S.C.; Allen, Adrian; McBride, S.H.; Skuce, Robin; Bermingham, M.; Woolliams, J.A. (BMC, 2017-06-24)

  Background: Susceptibility to Mycobacterium bovis infection in cattle is governed in part by host genetics. However, cattle diagnosed as infected with M. bovis display varying signs of pathology. The variation in ...
• The in vitro and ex vivo effect of Auranta 3001 in preventing Cryptosporidium hominis and Cryptosporidium parvum infection 

  Ch Stratakos, Alexandros; Sima, Filip; Ward, Patrick; Linton, Mark; Kelly, Carmel; Pinkerton, Laurette; Stef, Lavinia; Pet, Ioan; Iancu, Tiberiu; Pircalabioru, Gratiela; Corcionivoschi, Nicolae (BMC, 2017-08-31)

  Background: Cryptosporidium is a major cause of diarrhea worldwide in both humans and farm animals with no completely effective treatment available at present. In this study, we assessed the inhibitory effect of different ...
• The in vitro and in vivo effect of Carvacrol in preventing Campylobacter infection, colonisation and improve chicken broilers productivity 

  Kelly, Carmel; Gundogdu, Ozan; Pircalabioru, Gratiela; Cean, Ada; Scates, Pam; Linton, Mark; Pinkerton, Laurette; Magowan, Elizabeth; Stef, Lavinia; Simiz, Eliza; Pet, Ioan; Stewart, Sharon; Stabler, Richard; Wren, Brendan; Dorrell, Nick; Corcionivoschi, Nicolae (Mary Ann Liebert, 2017-06-01)

  The current trend in reducing the antibiotic usage in animal production imposes urgency in the identification of novel biocides. The essential oil carvacrol, for example, changes the morphology of the cell and acts against ...
• Needle-free delivery of measles virus vaccine to the lower respiratory tract of non-human primates elicits optimal immunity and protection 

  de Swart, Rik L.; de Vries, Rory D.; Rennick, Linda J.; van Amerongen, Geert; McQuaid, Stephen; Verburgh, R. Joyce; Yuksel, Selma; de Jong, Alwin; Lemon, Ken; Nguyen, D. Tien; Ludlow, Martin; Osterhaus, Albert D.M.E.; Duprex, W. Paul (Nature Research, 2017-08-01)

  Needle-free measles virus vaccination by aerosol inhalation has many potential benefits. The current standard route of vaccination is subcutaneous injection, whereas measles virus is an airborne pathogen. However, the ...
• Bovine tuberculosis visible lesions in cattle culled during herd breakdowns: the effects of individual characteristics, trade movement and co-infection 

  Byrne, Andrew W.; Graham, Jordon; Brown, Craig; Donaghy, Aoibheann; Guelbenzu Gonzalo, Maria; McNair, James; Skuce, Robin A.; Allen, Adrian; McDowell, Stanley W.J. (Springer, 2017-12)

  Background: Bovine tuberculosis (bTB), caused by Mycobacterium bovis, remains a significant problem for livestock industries in many countries worldwide including Northern Ireland, where a test and slaughter regime has ...
• A Review of the Strain Diversity and Pathogenesis of Chicken Astrovirus 

  Smyth, Victoria J. (MDPI, 2017-02-10)

  Although a relatively recently emerged virus, identified only in 2004 as a separate species of avian astrovirus, chicken astrovirus (CAstV) has been associated with poor growth of broiler flocks, enteritis and diarrhea and ...
• Detection of Tetrodotoxin Shellfish Poisoning (TSP) Toxins and Causative Factors in Bivalve Molluscs from the UK 

  Turner, Andrew D.; Dhanji-Rapkova, Monika; Coates, Lewis; Bickerstaff, Lesley; Milligan, Steve; O'Neill, Alison; Faulkner, Dermot; McEneny, Hugh; Baker-Austin, Craig; Lees, David N.; Algoet, Myriam (MDPI, 2017-08-30)

  Tetrodotoxins (TTXs) are traditionally associated with the occurrence of tropical Pufferfish Poisoning. In recent years, however, TTXs have been identified in European bivalve mollusc shellfish, resulting in the need to ...
• Intestinal microbiota profiles associated with low and high residual feed intake in chickens across two geographical locations 

  Siegerstetter, Sina-Catherine; Schmitz-Esser, Stephan; Magowan, Elizabeth; Wetzels, Stefanie Urimare; Zebeli, Qendrim; Lawlor, Peadar G.; O'Connell, Niamh E.; Metzler-Zebeli, Barbara U. (Public Library of Science, 2017-11-15)

  Intestinal microbe-host interactions can affect the feed efficiency (FE) of chickens. As inconsistent findings for FE-associated bacterial taxa were reported across studies, the present objective was to identify whether ...
• RAD sequencing resolves fine-scale population structure in a benthic invertebrate: implications for understanding phenotypic plasticity 

  Vendrami, David L.J.; Telesca, Luca; Weigand, Hannah; Weiss, Martina; Fawcett, Katie; Lehman, Katrin; Clark, M.S.; Leese, Florian; McMinn, Carrie; Moore, Heather M.; Hoffman, Joseph Il (Royal Society Publishing, 2017-02-01)

  The field of molecular ecology is transitioning from the use of small panels of classical genetic markers such as microsatellites to much larger panels of single nucleotide polymorphisms (SNPs) generated by approaches like ...
• Can We Breed Cattle for Lower Bovine TB Infectivity? 

  Tsairidou, Smaragda; Allen, Adrian; Banos, Georgios; Coffey, Mike; Anacleto, Osvaldo; Byrne, Andrew W.; Skuce, Robin; Glass, Elizabeth J.; Woolliams, John A.; Doeschl-Wilson, Andrea B. (Frontiers Media, 2018-12-07)

  Host resistance and infectivity are genetic traits affecting infectious disease transmission. This Perspective discusses the potential exploitation of genetic variation in cattle infectivity, in addition to resistance, ...
• Exploring the oxidative, antimicrobial and genomic properties of Campylobacter jejuni strains isolated from poultry 

  Ugarte-Ruiz, Maria; Domínguez, Lucas; Corcionivoschi, Nicolae; Wren, Brendan W.; Dorrell, Nick; Gundogdu, Ozan (Elsevier, 2018-06-19)

  Campylobacter jejuni is the leading cause of food-borne bacterial enteritis in humans, with contaminated poultry products considered the main source of infection. To survive the food chain, C. jejuni utilizes multiple ...
• The population and landscape genetics of the European badger (Meles meles) in Ireland 

  Guerrero, Jimena; Byrne, Andrew W.; Lavery, John; Presho, Eleanor; Kelly, Gavin; Courcier, Emily A.; O’Keeffe, James; Fogarty, Ursula; O’Meara, Denise B.; Ensing, Dennis; McCormick, Carl; Biek, Roman; Skuce, Robin; Allen, Adrian (Wiley, 2018-09-12)

  The population genetic structure of free-ranging species is expected to reflect landscape-level effects. Quantifying the role of these factors and their relative contribution often has important implications for wildlife ...
• The underlying microbial mechanism of epizootic rabbit enteropathy triggered by a low fiber diet 

  Jin, Ding Xing; Zou, Hua Wei; Liu, Si Qiang; Wang, Li Zhi; Xue, Bai; Wu, De; Tian, Gang; Cai, Jingyi; Yan, Tianhai; Wang, Zhi Sheng; Peng, Quan Hui (Nature Research, 2018-08-21)

  Epizootic rabbit enteropathy (ERE) is reproduced successfully in the present study by feeding rabbits a low-fibre diet, and high-throughput sequencing and quantitative real-time PCR (qPCR) analysis were applied to examine ...
• Feed Restriction Modulates the Fecal Microbiota Composition, Nutrient Retention, and Feed Efficiency in Chickens Divergent in Residual Feed Intake 

  Siegerstetter, Sina-Catherine; Petri, Renée M.; Magowan, Elizabeth; Lawlor, Peadar G.; Zebeli, Qendrim; O’Connell, Niamh E.; Metzler-Zebel, Barbara U. (Frontiers Media, 2018-11-19)

  There is a great interest to understand the impact of the gut microbiota on host’s nutrient use and FE in chicken production. Both chicken’s feed intake and gut bacterial microbiota differ between high and low-feed ...
• Evaluation of the methodological quality of studies of the performance of diagnostic tests for bovine tuberculosis using QUADAS 

  Downs, Sara H.; More, Simon J.; Goodchild, Anthony V.; Whelan, Adam O.; Abernethy, Darrell A.; Broughan, Jennifer M.; Cameron, Angus; Cook Alasdair J.; de la Rua-Domenech, R. Ricardo; Greiner, Matthias; Gunn, Jane; Nunez-Garcia Javier; Rhodes, Shelley; Rolfe, Simon; Sharp, Michael; Upton, Paul; Watson, Eamon; Welsh, Michael; Woolliams, John A.; Clifton-Hadley, Richard S.; Parry, Jessica E. (Elsevier, 2017-03-22)

  There has been little assessment of the methodological quality of studies measuring the performance (sensitivity and/or specificity) of diagnostic tests for animal diseases. In a systematic review, 190 studies of tests for ...
• Decision support beyond total savings—Eligibility and potential savings for individual participants from changes in the national surveillance strategy for bovine viral diarrhoea (BVD) in Ireland 

  Tratalos, Jamie A.; Thulke, Hans-Hermann; Graham, David A.; Guelbenzu Gonzalo, Maria; More, Simon J. (Elsevier, 2018-04-11)

  Surveillance and management of livestock diseases is often evaluated with reference to expected sector-wide costs. In contrast, we calculate losses or savings for individual herd owners of a change in monitoring strategy ...
• DIVA metabolomics: Differentiating vaccination status following viral challenge using metabolomic profiles 

  Gray, Darren W.; Welsh, Michael D.; Mansoor, Fawad; Doherty, Simon; Chevallier, Olivier P.; Elliott, Christopher T.; Mooney, Mark H. (Public Library of Science, 2018-04-05)

  Bovine Respiratory Disease (BRD) is a major source of economic loss within the agricultural industry. Vaccination against BRD-associated viruses does not offer complete immune protection and vaccine failure animals present ...
• Key actors in driving behavioural change in relation to on-farm biosecurity; a Northern Ireland perspective 

  Lahuerta-Marin, Angela; Brennan, M.L.; Finney, Graham; O'Hagan, M.J.H.; Jack, Claire G. (BMC, 2018-06-14)

  Background: Agriculture and farming are valued contributors to local economy in Northern Ireland (NI). There is limited knowledge about farmers’ behaviours and attitudes towards disease biosecurity measures. As part of a ...
• Effect of passive transfer status on response to a glycoprotein E (gE)-negative bovine herpesvirus type 1 (BoHV-1) and bovine respiratory syncytial virus (BRSV) vaccine and weaning stress in pre-weaned dairy calves 

  Dunn, Amanda; Welsh, Michael; Gordon, Alan Wesley; Arguello, Anastasio; Morrison, Steven J.; Earley, Bernadette (Taylor & Francis, 2018-01-09)

  The study objectives were to: 1) examine how calves of divergent immune status respond to BRSV vaccination at 3 weeks of age; 2) trace glycoprotein E negative BoHV-1 antibodies from vaccinated dams to calf sera and to ...
• An analysis of effects of heterozygosity in dairy cattle for bovine tuberculosis resistance 

  Tsairidou, S.; Allen, Adrian; Pong-Wong, R.; McBride, S.H.; Wright, D.M.; Matika, O.; Pooley, C.M.; McDowell, Stanley W.J.; Glass, E.J.; Skuce, Robin A.; Bishop, S.C.; Woolliams, J.A. (Wiley, 2018-01-24)

  Genetic selection of cattle more resistant to bovine tuberculosis (bTB) may offer a complementary control strategy. Hypothesising underlying non-additive genetic variation, we present an approach using genome-wide high ...

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