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An analysis of effects of heterozygosity in dairy cattle for bovine tuberculosis resistance

Tsairidou, S.; Allen, Adrian; Pong-Wong, R.; McBride, S.H.; Wright, D.M.; Matika, O.; Pooley, C.M.; McDowell, Stanley W.J.; Glass, E.J.; Skuce, Robin A.; Bishop, S.C.; Woolliams, J.A. (Wiley, 2018-01-24)

Genetic selection of cattle more resistant to bovine tuberculosis (bTB) may offer a complementary control strategy. Hypothesising underlying non-additive genetic variation, we present an approach using genome-wide high ...
Antimicrobial Properties of Basidiomycota Macrofungi to Mycobacterium abscessus Isolated from Patients with Cystic Fibrosis

Millar, Beverley Cherie; Nelson, David W. V. A.; Moore, Rachel E.; Rao, Juluri R.; Moore, John E. (Wolters Kluwer - Medknow, 2019-03-12)

Background: Antimicrobial resistance (AMR) has now emerged as a global public health crisis. Of particular concern is AMR associated with the genus Mycobacterium, including Mycobacterium tuberculosis and the nontuberculous ...
Antimicrobial resistance (AMR): significance to food quality and safety

Nelson, David W. V. A.; Moore, John E.; Rao, Juluri R. (Oxford University Press, 2019-04-09)

Antibiotic resistance presents a significant challenge to clinical, veterinary, and plant health and is now recognized by the World Health Organization (WHO) as a major emerging problem of global significance. As yet, ...
ATAC-Seq identifies regions of open chromatin in the bronchial lymph nodes of dairy calves experimentally challenged with bovine respiratory syncytial virus

Johnston, Dayle; JaeWoo, Kim; Taylor, Jeremy F.; Earley, Bernadette; McCabe, Matthew S.; Lemon, Ken; Duffy, Catherine; McMenamy, Michael; Cosby, S. Louise; Waters, Sinéad M. (BMC (Springer nature), 2021-01-06)

Background: Bovine Respiratory Syncytial Virus (BRSV) is a cause of Bovine Respiratory Disease (BRD). DNA-based biomarkers contributing to BRD resistance are potentially present in non-protein-coding regulatory regions ...
A Bayesian analysis of a Test and Vaccinate or Remove study to control bovine tuberculosis in badgers (Meles meles)

Arnold, Mark E.; Courcier, Emily A.; Stringer, Lesley A.; McCormick, Carl M.; Pascual-Linaza, Ana V.; Collins, Shane F.; Trimble, Nigel A.; Ford, Tom; Thompson, Suzan; Corbett, David; Menzies, Frazer D. (Public Library of Science (PLoS), 2021-01-28)

A novel five year Test and Vaccinate or Remove (TVR) wildlife research intervention project in badgers (Meles meles) commenced in 2014 in a 100km2 area of Northern Ireland. It aimed to increase the evidence base around ...
Bayesian latent class estimation of sensitivity and specificity parameters of diagnostic tests for bovine tuberculosis in chronically infected herds in Northern Ireland

Lahuerta-Marin, Angela; Milne, Georgina; McNair, James; Skuce, Robin; McBride, S.H.; Menzies, F.D.; McDowell, Stanley; Byrne, A.W.; Handel, I.G.; Bronsvoort, B.M. de C. (Elsevier, 2018-05-01)

In the European Union, the recommended ante-mortem diagnostic methods for bovine tuberculosis (bTB) include the single intradermal cervical comparative tuberculin (SICCT) test and the interferon-gamma (IFN- g) test as ...
Bovine Tuberculosis in Britain and Ireland – A Perfect Storm? the Confluence of Potential Ecological and Epidemiological Impediments to Controlling a Chronic Infectious Disease

Allen, Adrian; Skuce, Robin A.; Byrne, A.W. (Frontiers Media, 2018-06-05)

Successful eradication schemes for bovine tuberculosis (bTB) have been implemented in a number of European and other countries over the last 50 years. However, the islands of Britain and Ireland remain a significant ...
Bovine tuberculosis visible lesions in cattle culled during herd breakdowns: the effects of individual characteristics, trade movement and co-infection

Byrne, Andrew W.; Graham, Jordon; Brown, Craig; Donaghy, Aoibheann; Guelbenzu Gonzalo, Maria; McNair, James; Skuce, Robin A.; Allen, Adrian; McDowell, Stanley W.J. (Springer, 2017-12)

Background: Bovine tuberculosis (bTB), caused by Mycobacterium bovis, remains a significant problem for livestock industries in many countries worldwide including Northern Ireland, where a test and slaughter regime has ...
Can We Breed Cattle for Lower Bovine TB Infectivity?

Tsairidou, Smaragda; Allen, Adrian; Banos, Georgios; Coffey, Mike; Anacleto, Osvaldo; Byrne, Andrew W.; Skuce, Robin; Glass, Elizabeth J.; Woolliams, John A.; Doeschl-Wilson, Andrea B. (Frontiers Media, 2018-12-07)

Host resistance and infectivity are genetic traits affecting infectious disease transmission. This Perspective discusses the potential exploitation of genetic variation in cattle infectivity, in addition to resistance, ...
Challenges and Opportunities for Management of Crop and Tree Diseases in Northern Ireland

Rao, Juluri R.; Moore, John; Martin, Trevor; Nelson, David; Fleming, Colin (Scholars.Direct, 2020-10-24)

Phytopathogens have beleaguered the island of Ireland since the 19th century great famine caused by the potato blight oomycete, Phytophthora infestans and in recent times by cohorts of serious bacterial wilt diseases such ...
Characterisation of Cellulose Nanofibres Derived from Chemical and Mechanical Treatments

Muhamad, Martini; Hornsby, Peter; Carmichael, Eugene; Zakaria, Muhammad; Seok, Yew Been; Mohamed, Saiful; Sharma, Shekhar (EDP Sciences, 2019-01-14)

Optimised routes have been established to obtain high aspect ratio cellulose microfibrils derived from plant feedstocks, involving a combination of a chemical and mechanical treatment using a high pressure microfluidizer. ...
Climatic and evolutionary contexts are required to infer plant life history strategies from functional traits at a global scale

Kelly, Ruth; Healy, Kevin; Anand, Madhur; Baudraz, Maude E. A.; Bahn, Michael; Cerabolini, Bruno E. L.; Cornelissen, Johannes H. C.; Dwyer, John M.; Jackson, Andrew L.; Kattge, Jens; Niinemets, Ülo; Penuelas, Josep; Pierce, Simon; Salguero-Gómez, Roberto; Buckley, Yvonne M. (John Wiley & Sons, 2021-02-27)

Life history strategies are fundamental to the ecology and evolution of organisms and are 2 important for understanding extinction risk and responses to global change. Using global 3 datasets and a multiple response modelling ...
Co-infection status of novel parvovirus’s (PPV2 to 4) with porcine circovirus 2 in porcine respiratory disease complex and porcine circovirus-associated disease from 1997 to 2012

Lagan Tregaskis, Paula; Staines, Anthony; Gordon, Alan; Sheridan, Pauline; McMenamy, Michael; Duffy, Catherine; Collins, P. J.; Mooney, Mark H.; Lemon, Ken (Wiley, 2020-10-18)

As global pig health diseases, porcine respiratory disease complex (PRDC) and porcine circovirus-associated disease (PCVAD) generate substantial economic losses despite pigs been vaccinated against the primary causative ...
Comprehensive Longitudinal Microbiome Analysis of the Chicken Cecum Reveals a Shift From Competitive to Environmental Drivers and a Window of Opportunity for Campylobacter

Ijaz, Umer Zeeshan; Sivaloganathan, Lojika; McKenna, Aaron; Richmond, Anne; Kelly, Carmel; Linton, Mark; Stratakos, Alexandros Ch.; Lavery, Ursula; Elmi, Abdi; Wren, Brendan W.; Dorrell, Nick; Corcionivoschi, Nicolae; Gundogdu, Ozan (Frontiers Media, 2018-10-15)

Chickens are a key food source for humans yet their microbiome contains bacteria that can be pathogenic to humans, and indeed potentially to chickens themselves. Campylobacter is present within the chicken gut and is the ...
Decision support beyond total savings—Eligibility and potential savings for individual participants from changes in the national surveillance strategy for bovine viral diarrhoea (BVD) in Ireland

Tratalos, Jamie A.; Thulke, Hans-Hermann; Graham, David A.; Guelbenzu Gonzalo, Maria; More, Simon J. (Elsevier, 2018-04-11)

Surveillance and management of livestock diseases is often evaluated with reference to expected sector-wide costs. In contrast, we calculate losses or savings for individual herd owners of a change in monitoring strategy ...
Detection and characterization of chicken astrovirus associated with hatchery disease in commercial day‑old turkeys in southwestern Nigeria

Adebiyi, Adebowale I.; Mcilwaine, Kerry; Oluwayelu, Daniel O.; Smyth, Victoria J. (Springer Science and Business Media LLC, 2021-03-23)

Infectious diseases are a major obstacle to profitable poultry production in Nigeria due to the mortality and severe economic losses they cause. In particular, they are a potent threat to attainment of the food security ...
Detection of Tetrodotoxin Shellfish Poisoning (TSP) Toxins and Causative Factors in Bivalve Molluscs from the UK

Turner, Andrew D.; Dhanji-Rapkova, Monika; Coates, Lewis; Bickerstaff, Lesley; Milligan, Steve; O'Neill, Alison; Faulkner, Dermot; McEneny, Hugh; Baker-Austin, Craig; Lees, David N.; Algoet, Myriam (MDPI, 2017-08-30)

Tetrodotoxins (TTXs) are traditionally associated with the occurrence of tropical Pufferfish Poisoning. In recent years, however, TTXs have been identified in European bivalve mollusc shellfish, resulting in the need to ...
Determination of nucleotide and enzyme degradation in haddock (Melanogrammus aeglefinus) and herring (Clupea harengus) after high pressure processing

Karim, Nurul Ulfah; Kennedy, James Terence; Linton, Mark; Patterson, Margaret; Watson, Sally; Gault, Norman (Peer J, 2019-08-27)

Background The degradation of nucleotides and their enzymes had been widely used to evaluate fish freshness. Immediately after fish death, adenosine triphosphate (ATP) degrades into inosine-5-monophosphate (IMP) via ...
DIVA metabolomics: Differentiating vaccination status following viral challenge using metabolomic profiles

Gray, Darren W.; Welsh, Michael D.; Mansoor, Fawad; Doherty, Simon; Chevallier, Olivier P.; Elliott, Christopher T.; Mooney, Mark H. (Public Library of Science, 2018-04-05)

Bovine Respiratory Disease (BRD) is a major source of economic loss within the agricultural industry. Vaccination against BRD-associated viruses does not offer complete immune protection and vaccine failure animals present ...
Does Mycobacterium tuberculosis var. bovis survival in the environment confound bovine tuberculosis control and eradication? A literature review

Allen, Adrian; Ford, Tom; Skuce, Robin A. (Hindawi, 2021-02-05)

Bovine tuberculosis (bTB) is one of the globe’s most common, multihost zoonoses and results in substantial socioeconomic costs for governments, farming industries, and tax payers. Despite decades of surveillance and ...

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