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A Review of the Strain Diversity and Pathogenesis of Chicken Astrovirus

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dc.contributor.author Smyth, Victoria J.
dc.date.accessioned 2021-07-16T09:35:04Z
dc.date.available 2021-07-16T09:35:04Z
dc.date.issued 2017-02-10
dc.identifier http://hdl.handle.net/20.500.12518/314
dc.identifier.citation Smyth, V. (2017) ‘A Review of the Strain Diversity and Pathogenesis of Chicken Astrovirus’, Viruses, 9(2), p. 29. doi: 10.3390/v9020029. en_US
dc.identifier.issn 1999-4915
dc.identifier.uri https://doi.org/10.3390/v9020029
dc.description Publication history: Accepted - 25 January 2017; Published online - 10 February 2017. en_US
dc.description.abstract Although a relatively recently emerged virus, identified only in 2004 as a separate species of avian astrovirus, chicken astrovirus (CAstV) has been associated with poor growth of broiler flocks, enteritis and diarrhea and is a candidate pathogen in cases of runting stunting syndrome. More recently CAstV has been implicated in cases of two other diseases of broilers as the sole etiological agent, namely severe kidney disease of young broilers with visceral gout and the “White Chicks” hatchery disease. Examination of the strains of CAstV associated with the two latter diseases reveals they are closely related genetically. This review will discuss the pathogenesis of CAstV in relation to strain diversity and the effects of vertical versus horizontal transmission, virus load, co-infections and age of bird at infection, all factors that may impact upon disease severity. en_US
dc.description.sponsorship The author would like to thank the Department of Agriculture, Environment and Rural Affairs (DAERA) in Northern Ireland for supporting this review. en_US
dc.language.iso en en_US
dc.publisher MDPI en_US
dc.rights © 2017 by the author; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). en_US
dc.subject chicken astrovirus en_US
dc.subject strain diversity en_US
dc.subject pathogenesis en_US
dc.title A Review of the Strain Diversity and Pathogenesis of Chicken Astrovirus en_US
dc.type Article en_US
dcterms.dateAccepted 2017-01-25
dcterms.dateSubmitted 2017-01-04


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