DSpace Repository

Emergence of Salmonid Alphavirus Genotype 2 in Norway—Molecular Characterization of Viral Strains Circulating in Norway and Scotland

Show simple item record

dc.contributor.author Hjortaas, Monika J.
dc.contributor.author Fringuelli, Elena
dc.contributor.author Monjane, Aderito L.
dc.contributor.author Mikalsen, Aase B.
dc.contributor.author Jonassen, Christine M.
dc.contributor.author Savage, Paul D.
dc.date.accessioned 2021-10-06T09:53:47Z
dc.date.available 2021-10-06T09:53:47Z
dc.date.issued 2021-08-06
dc.identifier http://hdl.handle.net/20.500.12518/358
dc.identifier.citation Hjortaas, M. J., Fringuelli, E., Monjane, A. L., Mikalsen, A. B., Jonassen, C. M., Savage, P. and Sindre, H. (2021) ‘Emergence of Salmonid Alphavirus Genotype 2 in Norway—Molecular Characterization of Viral Strains Circulating in Norway and Scotland’, Viruses, 13(8), p. 1556. doi: 10.3390/v13081556. en_US
dc.identifier.issn 1999-4915
dc.identifier.uri https://doi.org/10.3390/v13081556
dc.description Publication history: Accepted - 29 July 2021; Published online - 6 August 2021. en_US
dc.description.abstract Pancreas disease (PD) and sleeping disease (SD), caused by an alphavirus, are endemic in European salmonid aquaculture, causing significant mortality, reduced growth and poor flesh quality. In 2010, a new variant of salmonid alphavirus emerged in Norway, marine salmonid alphavirus genotype 2 (SAV2). As this genotype is highly prevalent in Scotland, transmission through well boat traffic was hypothesized as one possible source of infection. In this study, we performed full-length genome sequencing of SAV2 sampled between 2006 and 2012 in Norway and Scotland, and present the first comprehensive full-length characterization of Norwegian marine SAV2 strains. We analyze their relationship with selected Scottish SAV2 strains and explore the genetic diversity of SAV. Our results show that all Norwegian marine SAV2 share a recent last common ancestor with marine SAV2 circulating in Scotland and a higher level of genomic diversity among the Scottish marine SAV2 strains compared to strains from Norway. These findings support the hypothesis of a single introduction of SAV2 to Norway sometime from 2006–2010, followed by horizontal spread along the coast. en_US
dc.description.sponsorship This research was funded by Norwegian Seafood Research Fund (FHF) grant 900799 en_US
dc.language.iso en en_US
dc.publisher MDPI en_US
dc.rights Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). en_US
dc.subject salmonid alphavirus en_US
dc.subject genotypes en_US
dc.subject SAV2 en_US
dc.subject aquaculture en_US
dc.subject Norway en_US
dc.subject Scotland en_US
dc.subject phylogeography en_US
dc.subject molecular epidemiology en_US
dc.subject pancreas disease en_US
dc.title Emergence of Salmonid Alphavirus Genotype 2 in Norway—Molecular Characterization of Viral Strains Circulating in Norway and Scotland en_US
dc.type Article en_US
dcterms.dateAccepted 2021-07-29
dcterms.dateSubmitted 2021-06-21


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search


Browse

My Account