Measles vaccination: Threat from related veterinary viruses and need for continued vaccination post measles eradication

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dc.contributor.authorCosby, S. Louise
dc.contributor.authorWeir, Leanne
dc.date.accessioned2021-06-09T11:28:53Z
dc.date.available2021-06-09T11:28:53Z
dc.date.issued2017-12-14
dc.descriptionPublication history: Accepted - 3 November2017; Published online - 14 December 2017en_US
dc.description.abstractMeasles virus (MV) is the only human virus within the morbillivirus genus of the Paramyxoviridae. The veterinary members are canine distemper virus (CDV), peste des petits ruminants virus (PPRV), Rinderpest Virus (RPV) as well as the marine morbilliviruses phocine distemper virus (PDV), dolphin morbillivirus (DMV) and porpoise morbillivirus (PMV). Morbilliviruses have a severe impact on humans and animal species. They confer diseases which have contributed to morbidity and mortality of the population on a global scale. There is substantial evidence from both natural and experimental infections that morbilliviruses can readily cross species barriers. Of most concern with regard to zoonosis is the more recently reported fatal infection of primates in Japan and China with strains of CDV which have adapted to this host. The close genetic relationship, shared cell entry receptors and similar pathogenesis between the morbilliviruses highlights the potential consequences of complete withdrawal of MV vaccination after eradication. Therefore, it would be prudent to continue the current MV vaccination. Ultimately development of novel, safe vaccines which have higher efficacy against the veterinary morbilliviruses is a priority. These would to protect the human population long term against the threat of zoonosis by these veterinary viruses.en_US
dc.identifierhttp://hdl.handle.net/20.500.12518/265
dc.identifier.citationCosby, S. L. and Weir, L. (2017) ‘Measles vaccination: Threat from related veterinary viruses and need for continued vaccination post measles eradication’, Human Vaccines & Immunotherapeutics, 14(1), pp. 229–233. doi: 10.1080/21645515.2017.1403677.en_US
dc.identifier.issn2164-554X
dc.identifier.urihttps://doi.org/10.1080/21645515.2017.1403677
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.rightsCopyright 2017 Taylor & Francis. This work is made available online in accordance with the publisher's policies. Please refer to any applicable terms of use of the publisher.en_US
dc.subjectcross species infectionen_US
dc.subjectmeaslesen_US
dc.subjectmorbillivirusen_US
dc.subjectvaccinationen_US
dc.subjectveterinary morbillivirusesen_US
dc.subjectzoonosisen_US
dc.titleMeasles vaccination: Threat from related veterinary viruses and need for continued vaccination post measles eradicationen_US
dc.typeArticleen_US
dcterms.dateAccepted2017-11-03
dcterms.dateSubmitted2017-11-03

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