Essential fatty acids as biomedicines in cardiac health

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dc.contributor.authorBalta, Igori
dc.contributor.authorStef, Lavinia
dc.contributor.authorPet, Ioan
dc.contributor.authorIancu, Tiberiu
dc.contributor.authorStef, Ducu
dc.contributor.authorCorcionivoschi, Nicolae
dc.date.accessioned2021-12-22T14:49:17Z
dc.date.available2021-12-22T14:49:17Z
dc.date.issued2021-10-14
dc.descriptionPublication history: Accepted - 13 October 2021; Published online - 14 October 2021.en_US
dc.description.abstractThe destructive impact of cardiovascular diseases on health, including heart failure, peripheral artery disease, atherosclerosis, stroke, and other cardiac pathological conditions, positions these health conditions as leading causes of increased global mortality rates, thereby impacting the human quality of life. The considerable changes in modern lifestyles, including the increase in food intake and the change in eating habits, will unavoidably lead to an unbalanced consumption of essential fatty acids, with a direct effect on cardiovascular health problems. In the last decade, essential fatty acids have become the main focus of scientific research in medical fields aiming to establish their impact for preventing cardiovascular diseases and the associated risk factors. Specifically, polyunsaturated fatty acids (PUFA), such as omega 3 fatty acids, and monounsaturated fatty acids from various sources are mentioned in the literature as having a cardio-protective role, due to various biological mechanisms that are still to be clarified. This review aims to describe the major biological mechanisms of how diets rich in essential fatty acids, or simply essential fatty acid administration, could have anti-inflammatory, vasodilatory, anti-arrhythmic, antithrombotic, antioxidant, and anti-atherogenic effects. This review describes findings originating from clinical studies in which dietary sources of FAs were tested for their role in mitigating the impact of heart disorders in human healthen_US
dc.identifierhttp://hdl.handle.net/20.500.12518/384
dc.identifier.citationBalta, I., Stef, L., Pet, I., Iancu, T., Stef, D. and Corcionivoschi, N. (2021) ‘Essential Fatty Acids as Biomedicines in Cardiac Health’, Biomedicines. MDPI AG. doi:10.3390/biomedicines9101466.en_US
dc.identifier.issn2227-9059
dc.identifier.urihttps://doi.org/10.3390/biomedicines9101466
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.rights© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/)en_US
dc.subjectcardiovascular diseasesen_US
dc.subjectessentially fatty acidsen_US
dc.subjectfatty acid sourcesen_US
dc.subjectcardiac healthen_US
dc.subjectmolecular mechanismsen_US
dc.subjectPFAen_US
dc.subjectomega-3en_US
dc.subjectEPA and DHAen_US
dc.subjectsymptom reliefen_US
dc.titleEssential fatty acids as biomedicines in cardiac healthen_US
dc.typeArticleen_US
dcterms.dateAccepted2021-10-13
dcterms.dateSubmitted2021-09-14

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